10 papers this month, half of which relate to the United Kingdom. We continue to move forward. 1) Characterization of opioid overdose and response in a high-risk community corrections sample: A preliminary study. Cropsey KL, Martin S, Clark CB, McCullumsmith CB, Lane PS, Hardy S, Hendricks PS, Redmond N. J Opioid Manag. 2013 Nov-Dec;9(6):393-400. Comments: Valuable surveyRead More
PubMed Update October 2013
A slight reprieve from the onslaught, only 6 articles this month – some of which are really interesting. 1) The Toxicology Investigators Consortium Case Registry-The 2012 Experience. Wiegand T, Wax P, Smith E, Hart K, Brent J. J Med Toxicol. 2013 Nov 1. [Epub ahead of print] Comments: Fascinating TocIC Registry, including cases that wereRead More
PubMed Update December 2012 – January 2013
This is a really exciting time for research into overdose in general and naloxone in particular. 15 papers this time. Opioid overdose rates and implementation of overdose education and nasalnaloxone distribution in Massachusetts: interrupted time series analysis. Walley AY, Xuan Z, Hackman HH, Quinn E, Doe-Simkins M, Sorensen-Alawad A, Ruiz S, Ozonoff A. BMJ. 2013Read More
PubMed Update October/November 2012
My apologies for tardiness. I’ll try to be on time next month. 13 papers described below. Prevention of fatal opioid overdose. Beletsky L, Rich JD, Walley AY. JAMA. 2012 Nov 14;308(18):1863-4. doi: 10.1001/jama.2012.14205. Comment: An excellent summary of key issues in overdose prevention and increasing naloxone availability for lay overdose reversal. Read it. Management ofRead More
PubMed Update September 2012
Another busy month in overdose-related research (11 papers), including several toxicology and epidemiology papers, some of which represent novel analytic approaches that serve to advance the field. Oxycodone overdose causes naloxone responsive coma and QT prolongation. Berling I, Whyte IM, Isbister GK. QJM. 2012 Sep 28. [Epub ahead of print] PMID: 23023890 [PubMed – as supplied by publisher] Comment:Read More
PubMed July 2012 Update
LOTS of great articles this month (10 total)! Let’s start with an updated chart of the number of scientific opioid overdose articles each year from 1980 through 2011. Injection Drug Users Trained by Overdose Prevention Programs: Responses to Witnessed Overdoses Lankenau SE, Wagner KD, Silva K, Kecojevic A, Iverson E, McNeely M, Kral AH. JRead More
PubMed June 2012 Update
jThis chart was produced in 2007 to demonstrate the increase in overdose literature in the late 1990s and early 2000s – a trend that has continued. Twenty years ago there would have been 1 article for this post every 3-4 months, which may have been okay since you would have received it by actual post.Read More
Pubmed May 2012 Update
This is actually an interim update because my last PubMed pull came up dry. We have papers from New Mexico, Serbia, and Italy, as well as a case report, addressing sociodemographics, depression, naltrexone, methadone, buprenorphine, and heart failure. 1) The influence of living along the U.S.-Mexico border on unintentional drug overdose death, New Mexico (USA), 2005-2009. Shah NG,Read More
Pubmed April 2012 Update
Here we go with April 2012 … Mortality and causes of death among users of methadone maintenance treatment in Israel, 1999-2008. Rosca P, Haklai Z, Goldberger N, Zohar P, Margolis A, Ponizovsky AM. Drug Alcohol Depend. 2012 Apr 6. [Epub ahead of print] Comment: Rate of overdose mortality was 0.22/100 person-years (i.e. 0.22%), one-quarter toRead More
Pubmed March 2012 Update
A number of good papers this month! Most notable are the MMWR report and the intriguing Copenhagen data on opioid overdoses attended by emergency medical services. Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds. Whelan PJ, Remski K. J Neurosci Rural Pract. 2012 Jan;3(1):45-50. Comment: Includes a brief reviewRead More