A robust 20 papers this month. There are some excellent manuscripts this month, including several on fentanyl. I want to draw particular attention to a few papers that will be important reads for some of you: #1 addresses concurrent use of methamphetamine with heroin, #12 explores different “types” of opioid overdose, #17 reviews the foundationalRead More
PubMed Update April 2016
23 for this month! Lots of interesting stuff, from large-scale epidemiology to randomized controlled trials. 1) Pharmacokinetic Properties and Human Use Characteristics of an FDA Approved IntranasalNaloxone Product for the Treatment of Opioid Overdose. Krieter P, Chiang N, Gyaw S, Skolnick P, Crystal R, Keegan F, Aker J, Beck M, Harris J. J Clin Pharmacol. 2016 MayRead More
PubMed Update March 2016
23 this month. 1) Are take-home naloxone programmes effective? Systematic review utilizing application of the Bradford Hill criteria. McDonald R, Strang J. Addiction. 2016 Mar 30. doi: 10.1111/add.13326. [Epub ahead of print] Review. Comments: Take-home naloxone meets all Bradford Hill criteria for causality in reducing opioid overdose mortality. Incidence of fatality among overdoses in the setting ofRead More
PubMed Update November 2015 – January 2016
We have 35 articles for your viewing this time, with apologies for the delay in getting this out. Thanks to Traci Green for offering to help out and for reviewing this post. 1) Management of patients with issues related to opioid safety, efficacy and/or misuse: a case series from an integrated, interdisciplinary clinic. Becker WC, MerlinRead More
PubMed Update March – May 2015
Three months. 46 papers. I’m already a month behind. 1) Development and implementation of intranasal naloxone opioid overdose response protocol at a homeless health clinic. Dahlem CH, Horstman MJ, Williams BC. J Am Assoc Nurse Pract. 2015 Mar 26. doi: 10.1002/2327-6924.12249. [Epub ahead of print] Comments: Naloxone programs have been providing kits to settings where homeless people receive servicesRead More
PubMed Update November 2014 – February 2015
Catching up on 51 papers in 4 months. Did you miss me? 1) New Drugs of Abuse. Rech MA, Donahey E, Cappiello Dziedzic JM, Oh L, Greenhalgh E. Pharmacotherapy. 2014 Dec 4. doi: 10.1002/phar.1522. [Epub ahead of print] Comment: Review of management of drug toxicities among novel, synthetic compounds. 2) Police officer attitudes towards intranasal naloxone training.Read More
PubMed Update: Another Year in Overdose
Another year in overdose, September 2012-August 2013, generally in reverse chronological order, and following the same loosely-formed categories as last year. Once again, this is opioid focused and misses anything not listed in the PubMed database – which means it misses many interesting papers to which you are warmly welcomed to post links! This yearRead More
PubMed Update August 2013
16 papers today – this is getting to be a big job. Naloxone, fentanyl, methadone, stars, pain, Central Asia, primary care, injection facilities, personal stories … 1) Notes from the field: acetyl fentanyl overdose fatalities – rhode island, march-may 2013. Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep. 2013 Aug 30;62(34):703-4.Read More
PubMed Update October/November 2012
My apologies for tardiness. I’ll try to be on time next month. 13 papers described below. Prevention of fatal opioid overdose. Beletsky L, Rich JD, Walley AY. JAMA. 2012 Nov 14;308(18):1863-4. doi: 10.1001/jama.2012.14205. Comment: An excellent summary of key issues in overdose prevention and increasing naloxone availability for lay overdose reversal. Read it. Management ofRead More
PubMed June 2012 Update
jThis chart was produced in 2007 to demonstrate the increase in overdose literature in the late 1990s and early 2000s – a trend that has continued. Twenty years ago there would have been 1 article for this post every 3-4 months, which may have been okay since you would have received it by actual post.Read More