49 in two months. Enjoy! 1) Multiple Fentanyl Overdoses – New Haven, Connecticut, June 23, 2016. Tomassoni AJ, Hawk KF, Jubanyik K, Nogee DP, Durant T, Lynch KL, Patel R, Dinh D, Ulrich A, D’Onofrio G. MMWR Morb Mortal Wkly Rep. 2017 Feb 3;66(4):107-111. doi: 10.15585/mm6604a4. Comments: Nice description of an outbreak of and publicRead More
PubMed Update October/November 2016
43 papers this round, and there are some goodies in here for sure (don’t miss #38!). Given the number and varied issues addressed, I divided them up into topic areas and, given the number on naloxone, I divided up the naloxone topic areas as well. Naloxone interventions Primary care 1) Co-prescription of naloxone as aRead More
PubMed Update September 2016
15 papers this month. 1) Drugs, Guns and Cars: How Far We Have Come to Improve Safety in the United States; Yet We Still Have Far to Go. Dodington J, Violano P, Baum CR, Bechtel K. Pediatr Res. 2016 Sep 27. doi: 10.1038/pr.2016.193. [Epub ahead of print] Review. Comment: Review of safety efforts in publicRead More
PubMed Update August 2016
A robust 20 papers this month. There are some excellent manuscripts this month, including several on fentanyl. I want to draw particular attention to a few papers that will be important reads for some of you: #1 addresses concurrent use of methamphetamine with heroin, #12 explores different “types” of opioid overdose, #17 reviews the foundationalRead More
PubMed Update July 2016
11 papers this month, including an announcement that naloxone is now over-the-counter in Australia. 1) Factors associated with knowledge of a Good Samaritan Law among young adults who use prescription opioids non-medically. Evans TI, Hadland SE, Clark MA, Green TC, Marshall BD. Harm Reduct J. 2016 Jul 26;13(1):24. doi: 10.1186/s12954-016-0113-2. Comments: Less than half knewRead More
PubMed Update June 2016
Summer holiday. A mere 10 articles this month! 1) Community pharmacist knowledge, attitudes and confidence regarding naloxone for overdosereversal. Nielsen S, Menon N, Larney S, Farrell M, Degenhardt L. Addiction. 2016 Jul 1. doi: 10.1111/add.13517. [Epub ahead of print] Comment: Most pharmacists in Australia would provide naloxone, but a minority feel comfortable selecting patients and educating about naloxoneRead More
PubMed Update May 2016
19 this month. Enjoy! 1) Methadone-Related Overdose Deaths in a Liberal Opioid Maintenance Treatment Programme. Tjagvad C, Skurtveit S, Linnet K, Andersen LV, Christoffersen DJ, Clausen T. Eur Addict Res. 2016 Jun 1;22(5):249-258. [Epub ahead of print] Comments: Patients on very high doses of methadone or also using benzodiazepines were at higher risk of death.Read More
PubMed Update April 2016
23 for this month! Lots of interesting stuff, from large-scale epidemiology to randomized controlled trials. 1) Pharmacokinetic Properties and Human Use Characteristics of an FDA Approved IntranasalNaloxone Product for the Treatment of Opioid Overdose. Krieter P, Chiang N, Gyaw S, Skolnick P, Crystal R, Keegan F, Aker J, Beck M, Harris J. J Clin Pharmacol. 2016 MayRead More
PubMed Update March 2016
23 this month. 1) Are take-home naloxone programmes effective? Systematic review utilizing application of the Bradford Hill criteria. McDonald R, Strang J. Addiction. 2016 Mar 30. doi: 10.1111/add.13326. [Epub ahead of print] Review. Comments: Take-home naloxone meets all Bradford Hill criteria for causality in reducing opioid overdose mortality. Incidence of fatality among overdoses in the setting ofRead More
PubMed Update February 2016
Ten articles for February 2016. 1) As opioid overdose deaths reach record highs, call for systematic changes grows louder. [No authors listed] ED Manag. 2016 Feb;28(2):13-9. Comments: Review of the new CDC opioid prescribing guidelines. 2) Australia reschedules naloxone for opioid overdose. Lenton SR, Dietze PM, Jauncey M. Med J Aust. 2016 Mar 7;204(4):146-7. No abstract available. Comments: Naloxone canRead More
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